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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PRKAA1
All Species:
29.09
Human Site:
S486
Identified Species:
53.33
UniProt:
Q13131
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q13131
NP_006242.5
559
64009
S486
D
E
I
T
E
A
K
S
G
T
A
T
P
Q
R
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001086285
574
65620
S501
D
E
I
T
E
A
K
S
G
T
A
T
P
Q
R
Dog
Lupus familis
XP_536491
563
64691
S490
D
E
I
T
E
A
K
S
G
T
A
T
P
Q
R
Cat
Felis silvestris
Mouse
Mus musculus
Q5EG47
559
63911
S486
D
E
I
T
E
A
K
S
G
T
A
T
P
Q
R
Rat
Rattus norvegicus
P54645
559
63955
S486
D
E
I
T
E
A
K
S
G
T
A
T
P
Q
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506315
519
59478
R453
S
G
T
T
T
P
Q
R
S
G
S
V
S
N
Y
Chicken
Gallus gallus
Q9IA88
798
88848
E653
E
G
R
N
L
L
E
E
V
L
Q
Q
Q
R
M
Frog
Xenopus laevis
NP_001083882
560
64031
S487
D
E
V
T
E
S
K
S
E
S
A
T
P
R
R
Zebra Danio
Brachydanio rerio
NP_001103756
573
65002
S480
D
D
M
M
E
V
K
S
G
T
A
T
P
H
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_623371
515
58559
T451
V
R
Q
K
N
K
L
T
D
R
Y
S
K
M
S
Nematode Worm
Caenorhab. elegans
Q95ZQ4
626
70425
S545
D
E
E
S
G
S
A
S
A
S
S
S
R
H
A
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q38997
535
61163
H469
G
M
L
S
N
S
M
H
D
N
N
Y
F
G
D
Baker's Yeast
Sacchar. cerevisiae
P06782
633
72027
K567
E
K
I
P
D
L
M
K
M
V
I
Q
L
F
Q
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
97.2
92.5
N.A.
98.7
99.1
N.A.
89.2
27
88.7
84.4
N.A.
N.A.
62.2
53.5
N.A.
Protein Similarity:
100
N.A.
97.3
93.7
N.A.
99.4
99.6
N.A.
91
43.1
94.6
90.9
N.A.
N.A.
75.1
66.4
N.A.
P-Site Identity:
100
N.A.
100
100
N.A.
100
100
N.A.
6.6
0
66.6
66.6
N.A.
N.A.
0
20
N.A.
P-Site Similarity:
100
N.A.
100
100
N.A.
100
100
N.A.
20
20
93.3
80
N.A.
N.A.
13.3
53.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
45
33.4
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
62.4
51.9
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
39
8
0
8
0
54
0
0
0
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
62
8
0
0
8
0
0
0
16
0
0
0
0
0
8
% D
% Glu:
16
54
8
0
54
0
8
8
8
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
8
8
0
% F
% Gly:
8
16
0
0
8
0
0
0
47
8
0
0
0
8
0
% G
% His:
0
0
0
0
0
0
0
8
0
0
0
0
0
16
0
% H
% Ile:
0
0
47
0
0
0
0
0
0
0
8
0
0
0
0
% I
% Lys:
0
8
0
8
0
8
54
8
0
0
0
0
8
0
0
% K
% Leu:
0
0
8
0
8
16
8
0
0
8
0
0
8
0
0
% L
% Met:
0
8
8
8
0
0
16
0
8
0
0
0
0
8
8
% M
% Asn:
0
0
0
8
16
0
0
0
0
8
8
0
0
8
0
% N
% Pro:
0
0
0
8
0
8
0
0
0
0
0
0
54
0
0
% P
% Gln:
0
0
8
0
0
0
8
0
0
0
8
16
8
39
8
% Q
% Arg:
0
8
8
0
0
0
0
8
0
8
0
0
8
16
54
% R
% Ser:
8
0
0
16
0
24
0
62
8
16
16
16
8
0
8
% S
% Thr:
0
0
8
54
8
0
0
8
0
47
0
54
0
0
0
% T
% Val:
8
0
8
0
0
8
0
0
8
8
0
8
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
8
8
0
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _